Fast, copper-free click chemistry: a convenient solid-phase approach to oligonucleotide conjugation.
نویسندگان
چکیده
Solid-phase oligonucleotide conjugation by nitrile oxide-alkyne click cycloaddition chemistry has been successfully demonstrated; the reaction, compatible with all nucleobases, requires no metal catalyst and proceeds under physiological conditions.
منابع مشابه
Oligonucleotide tagging for copper-free click conjugation.
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ورودعنوان ژورنال:
- Chemical communications
دوره 22 شماره
صفحات -
تاریخ انتشار 2009